In an effort to make Oligopaint FISH probes more broadly available to the research community, we offer DNA and RNA FISH probe design, synthesis, and generation. By dedicating a full-time staff member to this initiative, we aim to lower barriers for labs interested in applying FISH-based imaging to their own systems, regardless of prior experience with probe development.
What We Offer
- Probe Library Design & Synthesis
We design custom probe sets tailored to your genomic region of interest and provide high-fidelity oligo libraries. Our approach allows flexibility in scale, from small targeted regions to entire chromosomes. - Experiment-Ready Probe Generation
We deliver ready-to-use probes, including fluorophore incorporation, amplification, and quality control validation. This ensures that probes arrive ready for immediate use in FISH experiments. - Image Analysis Services
Our team provides computational support, offering standardized image analysis pipelines for segmentation, spot detection, and quantitative measurements.
How It Works
- Initial Consultation – Our technician will work with you to understand your research goals and design parameters.
- Custom Design & Synthesis – Probe libraries are designed and synthesized according to your specifications.
- Optional Probe Generation & Analysis – Depending on your needs, we can prepare experiment-ready probes and provide downstream image analysis services.
📩 For details on pricing, please contact us directly at Oligopaint Requests.
The Joyce Lab at UPENN 